Position: Principal Formulation Scientist

Position Summary

Expected Salary: At or Above Market Rate

Work Location: Hangzhou, China

Seniority Level: Mid-Senior level

Employment Type: Full-Time

 

METiS is seeking an experienced, innovative, impactful, entrepreneurial and highly talented individual to lead our Formulation Development efforts. The candidate will lead a cross-disciplinary team of chemists, software and hardware engineers to realize our vision of building the world’s first AI-driven drug formulation platform. Cross-functional collaboration and a mind-set of innovation are critical to this role. The position will also lead projects within a broad therapeutic platform. The ideal applicant will be an experienced scientist with a strong background in formulations across various technologies, such as solutions, emulsions, solid dispersion, inclusion complexation, nanoparticles, and other delivery systems. Top applicant will possess a proven track record of leading successful development of clinical formulations.

The level of the role will be determined (Senior Scientist/Principal Scientist/Director of Formulation Development) commensurate with experience and qualifications.

 

Key responsibilities

  • Lead a team of chemists, machine learning scientist, automation engineer, and computational chemist to develop the AI-driven formulation platform

  • Lead one or more of formulation and delivery system development programs focusing on poorly soluble small molecule drugs

  • Act as the formulation/delivery subject matter expert on the broader project team focused on advancing 505(b)(2) drug candidates to clinical stage

  • Work with internal project team and CROs to supply appropriate formulations for in vivo studies

  • Generate and support generation of IP for core projects

  • Ultimately develop formulations, processes and documentation to support GLP toxicology, GMP manufacturing, and regulatory filings

 

Qualifications

  • Ph.D. in Physical Organic Chemistry, Chemical Engineering, Pharmaceutical Sciences/Engineering or related discipline with 4+ years of industry experience, or

  • BS/MS with 8+ years of industry experience

  • Experience in designing, developing and optimizing formulation for small molecule drugs, working across various technologies, such as solution, emulsions, solid dispersion, inclusion complexation, nano-crystal, and other delivery systems

  • A proven track record of successful development of drug product

  • Proficiency with a broad spectrum of analytical techniques (i.e. PXRD, HPLC, etc.)

 

Preferred Qualifications

  • Demonstrated ability in working with highly skilled teams in a fast paced, entrepreneurial and technical setting

  • Familiar with statistical or simulation tools

  • Highly adaptable and responsive to technical and business opportunities- comfortable delivering against challenging commitments

  • Experience with biologics, mRNA or gene therapy is a plus

All interested candidates please send resume and cover letter  (中英文都可以) to hr@metispharmaceuticals.com